While New York City (NYC) is the epicenter of the AIDS pandemic in the United States, Bedford-Stuyvesant is the epicenter of the pandemic for African-Americans, adolescents, infants and children. Twenty-four percent of individuals living with AIDS in Brooklyn live in Bedford-Stuyvesant.
United Hospital Fund(UHF) Neighborhoods AIDS data is reported by zip code and the NYC Department of Health (DOH) generally reports AIDS statistics using the  (UHF) zip code clusters. For UHF Bedford-Stuyvesant, Crown Heights (UHF Bed-Stuy), the cluster includes zip codes 11212, 11213, 11216,11233 and 11238.
UHF Bed-Stuy with 13% of the adult population has 6,761 (23%) of Brooklyn’s diagnosed AIDS cases at the end of March 2000 – the largest percentage of all UHF neighborhoods in Brooklyn. At 2,792, UHF Bed-Stuy also has the second-highest case rate per 100,000 population
UHF Bed-Stuy had more residents diagnosed with  AIDS than New Orleans, Louisiana, 22nd in the nation, the entire state of Mississippi and 30 other states. At 2,792, UHF Bed-Stuy has more PLWAs than the state of Nevada and 25 other states.
UHF Bed-Stuy-Crown Heights ranked 1st in Brooklyn in the rate of all three reported STDs: gonorrhea, chlamydia and P & S Syphilis. Bed-Stuy-Crown Heights ranked 3rd for the rate of gonorrhea, 6th for chlamydia and 11th for P & S syphilis in NYC.
 The Community Needs Index (CNI)
Developed by the New York State Department of Health AIDS Institute, the CNI is a composite measure of service needs at the zip code level “to help users identify and direct health care and prevention services to communities most in need of such services.”
In the unpublished 2000 CNI, all zip codes in Bedford-Stuyvesant/CD3, except 11213 (“moderate need”), ranked “high need.”
Zip code 11216 ranked first of 37 in Brooklyn and 19th of the 177 zip codes for NYC.
Zip codes 11233, 11212, 11238 and 11213 ranked 3rd, 5th, 6th and 10th in Brooklyn, respectively, while ranking 24th, 30th, 32nd and 43rd, respectively in NYC.
Zip code 11216 also rated in the top 20% for all-risk indicator rates, as well as HIV infection and AIDS case rates. 11233 ranked in the top 20% for all risk indicators as well. All five zip codes in UHF B-S/CH ranked in the top ten of the CNI score out of the 37 zip codes in Brooklyn.